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Physiology and Modelling of the Visual System

(mostly old work)
Contact person:  Wörgötter, Florentin 

Computational Neuroscience

visualpathway_big

This project concerns electrophysiology as well as modelling.


Electrophysiology: Here we have recorded cells from the visual cortex and the thalamus (LGN) focusing on several questions:

  1. The action of intracortical inhibition on direction and orientation selectivity of cortical cells (1987-1990)

  2. The influence of cortico-thalamic projections on the cell responses in the LGN (1990-2000)

  3. The influence of the state of arousal on the cell behaviour in the LGN (1995-2000) and the cortex (1998-2000)

  4. The effect of stochastic resonance on visual cortical responses (2004-ongoing)


Modelling: Here we are mainly concerned with large biophysical models of different part of the visual system:

  1. Models of the visual cortex (1990-1995)

  2. Models of the interactions between visual cortex and thalamus, mostly focusing on receptive field changes due to cortico-thalamic influences and/or influences of the state of arousal or attentiveness, respectively (1995-2000)

  3. Detailed model of the Retina (2002-ongoing)

retina

Main cooperation partners:




Belongs to Group(s):
Computational Neuroscience

Funke, K, Kerscher, N, and Wörgötter, F (in revision).
Noise-improved signal detection in cat primary visual cortex via a well balanced stochastic resonance like process
Europ. J. Neurosci.. download file

Hennig, M, and Wörgötter, F (2007).
On the effect of fixational eye movements on the expression of retinal ganglion cell nonlinearities
J. Computat. Neurosci.. download file

Calow, D, Krueger, N, Wörgötter, F, and Lappe, M (2005).
Biologically motivated space-variant filtering for robust optic flow processing.
Network: Computation in Neural Systems 16(4):323-340. download file

Calow, D, Krüger, N, Wörgötter, F, and Lappe, M (2004).
Space variant filtering of optic flow for robust three dimensional motion estimation
In: Fourth International ICSC Symposium on Engineering of Intelligent Systems. Madeira, Madeira, Portugal, pages ". download file

Hennig, M, and Wörgötter, F (2004).
Eye micro-movements improve stimulus detection beyond the Nyquist limit in the peripheral retina
Advances in Neural Information Processing Systems 16. download file

Wörgötter, F, Krüger, N, Pugeault, N, Calow, D, Lappe, M, Pauwels, K, Van Hulle, M, Tan, S, and Johnston, A (2004).
Early cognitive vision: Using Gestalt laws for task-dependent, active image processing
Natural Computing 3:293–321. download file

Eyding, D, Macklis, JD, Neubacher, U, Funke, K, and Wörgötter, F (2003).
Selective elimination of corticogeniculate feedback abolishes the electroencephalogram dependence of primary visual cortical receptive fields and reduces their spatial specificity
J. Neurosci. 23(18):7021--7033. download file

Wörgötter, F, Suder, K, Pugeault, N, and Funke, K (2003).
Response characteristics in the lateral geniculate nucleus and their primary afferent influences on the visual cortex of cat
Modulation of Neuronal Responses: Implications for Active Vision. (G T Buracas, O Ruksenas, G M Boyton and T D Albright, eds.) NATO Science Series 1: Life and Behavioral Sciences 334:165–188.

Dahlem, M, and Wörgötter, F (2002).
Dynamical retino-cortical mapping
Workshop on Dynamic Perception, Bochum. download file

Dahlem, M, and Wörgötter, F (2002).
Rotation-invariant optical flow by gaze-depending retino-cortical mapping
Lecture Notes in Computer Science 2525:137-145. download file

Funke, K, Kisvarday, Z, Volgushev, M, and Wörgötter, F (2002).
Integrating anatomy and physiology of the primary visual pathway: from LGN to Cortex
In: Models of Neural Networks IV, edited by L v. Hemmen. Springer, pages 97-171.

Hennig, M, Funke, K, and Wörgötter, F (2002).
The influence of different retinal sub-circuits on the non-linearity of ganglion cell behavior
J. Neurosci. 22:8726-8738. download file

Hennig, M, Kerscher, N, Funke, K, and Wörgötter, F (2002).
Stochastic resonance in visual cortical neurons: Does the eye-tremor actually improve visual acuity?
Neurocomputing 44-46:115-120. download file

Suder, K, Funke, K, Zhao, Y, Kerscher, N, Eysel, U, Wennekers, T, and Wörgötter, F (2002).
Spatial dynamics of receptive fields in cat primary visual cortex related to the temporal structure of thalamo-cortical feed-forward activity – experiments and models
Exp. Brain Res. 144:430-444. download file

Wörgötter, F, Eyding, D, Macklis, JD, and Funke, K (2002).
The influence of the corticothalamic projection on responses in thalamus and cortex
Phil. Trans. R. Soc. Lond. B -(-):1823–1834. download file

Suder, K, and Wörgötter, F (2001).
Modeling motion induction to analyze connectivity in the early visual system
Neurocomputing 34-35:612-618. download file

Wörgötter, F (2001).
Bad design and good performance: Strategies of the visual system for enhanced image analysis
In: In Proc. Artificial Neural Networks, ICANN 2001 Vienna, edited by Dorffner, Bischof and Hornick. Springer, pages 13-15. download file

Quill, U, Funke, K, and Wörgötter, F (2000).
Investigations on emergent spatio-temporal neural response characteristics in a small network model
Biol. Cybern. 83:461–470. download file

Suder, K, and Wörgötter, F (2000).
The control of low level information flow in the visual system
Rev. Neurosci. 11:127–146. download file

Suder, K, Wennekers, T, and Wörgötter, F (2000).
Neural field model of receptive field restructuring in primary visual cortex
Neural Comp. 12:1–21. download file

Suder, K, Wennekers, T, and Wörgötter, F (2000).
Neural field description of state-dependent receptive field changes
Neurocomputing 32-33:545–551. download file

Wörgötter, F, and Eysel, UT (2000).
The effects of context and state on receptive fields in the striate cortex
TINS 23:497–503. download file

Li, B, Funke, K, Wörgötter, F, and Eysel, UT (1999).
Correlated variations in EEG pattern and visual responsiveness of cat lateral geniculate relay cells
J. Physiol. 514.3:857–874. download file

Suder, K, Wörgötter, F, and Wenneckers, T (1999).
Neural field description suggests feedforward mechanism of state-dependent visual receptive field changes
In: Proc. ICANN99. (Edinburgh), pages 67-72.

Suder, K, Wenneckers, T, and Wörgötter, F (1999).
Neural Field description of state-dependent receptive field changes in the visual cortex
In: Proc. ESANN99, edited by Verleysen, M. (Bruges), pages 171-176.

Wörgötter, F (1999).
Comparing different modeling approaches of visual cortical cell characteristics
Cerebral Cortex 13:201–249.

Wörgötter, F, Suder, K, and Funke, K (1999).
The dynamic spatio-temporal behavior of visual responses in thalamus and cortex
Restor Neurol Neurosci 15(2-3):137–152. download file

Köhn, J, and Wörgötter, F (1998).
Employing the Z-Transform to optimize the calculation of the synaptic conductance of NMDA- and other channels in network simulations
Neural Comp. 10:1639–1651. download file

Opara, R, and Wörgötter, F (1998).
A fast and robust cluster update algorithm for image segmentation in spin-lattice models without annealing – visual latencies revisited
Neural Comp. 10:1547–1566. download file

Quill, U, Wörgötter, F, Funke, K, and Lansner, A (1998).
The role of spatio-temporal structures in the formation of synchrony
In: Perspectives in neural computing, Proc. ICANN98, edited by Niklasson, L and Boden, M and Ziemke, T. (Skovde), pages 997-1002.

Suder, K, Funke, K, and Wörgötter, F (1998).
State-dependent spatio-temporal restructuring of receptive fields in the primary visual pathway
In: Perspectives in neural computing Proc. ICANN98, edited by Niklasson, L and Boden, M and Ziemke, T. (Skovde), pages 331-336.

Wörgötter, F, Nelle, E, Li, B, and Funke, K (1998).
The influence of corticofugal feedback on the temporal structure of visual responses of cat thalamic relay cells
J. Physiol. 509:797–815. download file

Wörgötter, F, Nelle, E, Li, B, Wang, L, and Diao, Y- (1998).
Linearity of spatial summation in simple cells: Experiments and Models
Exp. Brain Res. 122:318–332. download file

Wörgötter, F, Suder, K, Zhao, Y, Kerscher, N, Eysel, U, and Funke, K (1998).
State-dependent receptive field restructuring in the visual cortex
Nature 396:165–168. download file

Funke, K, and Wörgötter, F (1997).
The temporal dynamics of cell responses in the lateral geniculate nucleus
Prog in Neurobiol 13:67–119. download file

Opara, R, and Wörgötter, F (1997).
Introducing Visual Latencies into Spin-Lattice Models for Image Segmentation: A Neuromorphic Approach to a Computer Vision Problem
In: ICNN97. Houston, Texas, pages 2300-2303.

Funke, K, Nelle, E, Li, B, and Wörgötter, F (1996).
Corticofugal feedback improves the timing of retino-geniculate signal transmission
NeuroReport 7:2130–2134.

Köhn, J, and Wörgötter, F (1996).
Corticofugal feedback can reduce the visual latency of responses to antagonistic stimuli
Biol. Cybern. 75:199-209. download file

Opara, R, and Wörgötter, F (1996).
Utilizing latency for object recognition in artificial neural networks
Neural Comp. 8:1493-1520. download file

Wörgötter, F, Opara, R, Funke, K, and Eysel, UT (1996).
Utilizing latency for object recognition in real and artificial neural networks
NeuroReport 7:741-744.

Funke, K, and Wörgötter, F (1995).
Differences in the temporal dynamics of the visual ON- and OFF-pathways
Exp. Brain Res. 104:171-176.

Funke, K, and Wörgötter, F (1995).
Temporal structure in the light response of relay cells in the dorsal lateral geniculate nucleus of the cat
J Physiol 485:715–737.

Köhn, J, and Wörgötter, F (1995).
Latency-reduction in antagonistic visual channels as the result of corticofugal feedback
In: Symp. Artif. Neural Networks, edited by Verleysen, M. D-Facto, Brussels, pages 205-210.

Opara, R, and Wörgötter, F (1995).
Improving object recognition by using a visual latency mechanism
In: Europ. Symp. Artif. Neural Networks, edited by Verleysen, M. D-Facto, Brussels, pages 187-192.

Wörgötter, F, and Funke, K (1995).
Fine structure analysis of temporal patterns in the light response of cells in the lateral geniculate nucleus of cat
Vis Neurosci 12(3):469–484.

Wörgötter, F, Nelle, E, Li, B, Wang, L, and Diao, Y (1995).
Spatial summation in simple cells: Computational and experimental results
In: Europ. Symp. Artif. Neural Networks, edited by Verleysen, M. D-Facto, Brussels, pages 81-86.

Crook, JM, Wörgötter, F, and Eysel, UT (1994).
Velocity invariance of preferred axis of motion for single spot stimuli in simple cells of cat striate cortex
Exp Brain Res 102(1):175–180.

Eysel, U, Kisvarday, Z, Wörgötter, F, and Crook, J (1994).
Large basket cells and lateral inhibition in cat visual cortex.
In: Structural and Functional Organization of the Neocortex., edited by Albowitz, B. et al. (Eds.). Springer,Heidelberg, pages 212-220,.

Niebur, E, and Wörgötter, F (1994).
Design principles of columnar organization in visual cortex
Neural Comp 6:602-614.

Nelle, E, and Wörgötter, F (1993).
Cascaded intracortical inhibition: Modelling connection schemes on a large scale simulator
In: ICANN 93, Proc. Int. Conf.. ICANN, pages 157-160 ,.

Niebur, E, and Wörgötter, F (1993).
Orientation columns from first principles
In: F. Eeckman, Ed.. Kluver Academic, pages 409-414 ,.

Wörgötter, F, and Niebur, E (1993).
Cortical column design: A link between the maps of preferred orientation and orientation tuning strength?
Biol. Cybern. 70:1-13.

Eysel, UT, and Wörgötter, F (1992).
Horizontal intracortical contributions to functional specificity in cat visual cortex
In: Information Processing in the Cortex. Experiment and Theory., edited by A.Aertsen and V. Braitenberg. Springer, pages 301-323 ,.

Huck, M, Wörgötter, F, and Eysel, U (1992).
A processor ring for the implementation of neural networks with cortical architecture
In: , edited by I.Aleksander and J.Taylor. Elsevier Science Publishers B.V., pages 1435-1438 ,.

Niebur, E, and Wörgötter, F (1992).
Simulating the cat visual system on the connection machine
In: Los Alamos Publication Series. Los Alamos Publication Series, pages ,.

Wörgötter, F, Niebur, E, and Koch, C (1992).
Generation of direction selectivity by isotropic intracortical connections
Neural Comp 4:332-340.

Niebur, E, Wörgötter, F, and Koch, C (1991).
The Caltech computer cat: A fine-grain simulator of the primary visual system of cat.
In: Annales du Carnac.4. Carnac, pages 1-7 ,.

Niebur, E, Wörgötter, F, and Koch, C (1991).
Influence of the column structure on intracortical long-range interactions
In: Proc. 3rd Mid-Western Conf. on Neural Networks, edited by S. Samir. Purdue Univ. Press, W. Lafayett, pages ,.

Wörgötter, F, and Eysel, UT (1991).
Topographical aspects of the contributions of intracortical excitation and inhibition to orientation specificity in area 17 of the cat visual cortex
Europ. J. Neurosci. 3:1232–1244.

Wörgötter, F, and Eysel, UT (1991).
Axial responses in visual cortical cells. Spatio-temporal mechanisms quantified by Fourier components of cortical tuning curves
Exp. Brain Res. 83:656–664.

Wörgötter, F, and Holt, G (1991).
Spatio-temporal mechanisms in receptive fields of visual cortical simple cells: A model
J. Neurophysiol. 65:494-510. download file

Wörgötter, F, and Koch, C (1991).
A detailed model of the primary visual pathway in the cat: comparison of afferent excitatory and intracortical inhibitory connection schemes for orientation selectivity
J Neurosci 11(7):1959–1979. download file

Wörgötter, F, Muche, T, and Eysel, UT (1991).
Correlations between directional and orientational tuning of cells in cat striate cortex
Exp Brain Res 83(3):665–669.

Wörgötter, F, Niebur, E, and Koch, C (1991).
Isotropic connections generate functional asymmetrical behavior in visual cortical cells.
J. Neurophysiol. 66:444-459. download file

Niebur, E, and Wörgötter, F (1990).
Sharpening of orientation selective receptive fields in the mammalian visual cortex by long-range interactions
In: Proc. of the German Workshop on Artificial Intelligence (GWAI-90). GWAI, pages ,.

Niebur, E, and Wörgötter, F (1990).
Circular inhibition: A new concept in long-range interactions in the mammalian visual cortex
In: Proc. IJCNN'90, San Diego. Edward Brothers, Ann Arbor, pages II-367 - II-371 ,.

Wörgötter, F, Gründel, O, and Eysel, UT (1990).
Quantification and comparison of cell properties in cat's striate cortex determined by different types of stimuli
Europ. J. Neurosci. 2:928–941.

Wörgötter, F, Niebur, E, and Koch, C (1990).
Modeling visual cortex: Hidden anisotropies in an isotropic inhibitory connection scheme
In: Advanced Neural Computers, edited by R. Eckmiller. Elsevier Amsterdam, pages 87-95 ,.

Wörgötter, F, Kammen, D, and Brandt, B (1990).
Temporal dynamics in neuronal microcircuitry
In: Parallel Processing in Neural Systems and Computers, edited by R. Eckmiller, G. Hartmann and G. Hauske. Elsevier, Netherlands, pages 147-150 ,.

Wörgötter, F, and Eysel, UT (1989).
Axis of preferred motion is a function of bar length in visual cortical receptive fields
Exp. Brain Res. 76:307–314.

Eysel, UT, Muche, T, and Wörgötter, F (1988).
Lateral interactions at cat's direction selective striate neurones demonstrated by local cortical inactivation
J. Physiol. 399:657–675.

Wörgötter, F, and Eysel, UT (1988).
A simple glass coated, fire-polished tungsten electrode with impedance adjustment using hydrofluoridic acid
J. Neurosci. Meth. 25:135–138.

Eysel, UT, Wörgötter, F, and Pape, HC (1987).
Local cortical lesions abolish lateral inhibition at direction selective cells in cat visual cortex
Exp. Brain Res. 68:606–612.

Wörgötter, F, and Eysel, UT (1987).
Quantitative determination of orientational and directional components in the response of visual cortical cells to moving stimuli
Biol. Cybern. 57:349–355.

Wörgötter, F, Daunicht, WJ, and Eckmiller, R (1986).
An on-line spike form discriminator based on an analog correlation technique
J. Neurosci. Meth. 17:141–151.